Moving nearly $2 trillion worth of goods every year, FedEx is deeply connected to the flow of global trade. Facing unpredictable tariffs, fleet disruptions, and intense competition, the company is entering a new era of reglobalization, where automated belt systems, edge robotics, and new trade patterns are rewriting the rules of global supply chains. In a new episode of Fortune 500: Titans and Disruptors of Industry, Fortune’s Editor-in-Chief Alyson Shontell sat down with FedEx CEO Raj Subramaniam to discuss his rise within the company from the lowest level possible up to the CEO seat; how he’s overhauling the logistics company and taking it through three transformations; and how he’s thinking about AI, robotics, and the future of the company. On reglobalization and trade disruption - Why Subramaniam says tariffs and geopolitics are reshaping global trade, driving growth in Latin America, Southeast Asia, and India. On FedEx’s transformation - How FedEx is uniting its Express and Ground networks, simplifying the organization, and building digital capabilities for e-commerce. On AI and the value of FedEx data - How FedEx is using its data and AI to optimize deliveries, improve customs support, predict disruptions, and serve high-value supply chains. - Why Subramaniam sees FedEx’s logistics intelligence as a potential source of new services and revenue. On robotics and autonomy - How FedEx is testing autonomous trucks with Aurora, starting with highway routes. - How Dexterity and Berkshire Grey are helping automate truck loading and unloading in FedEx hubs. On preserving the FedEx culture - Why Subramaniam says FedEx’s “People, Service, Profit” model and its “Purple Promise” remain the company’s foundation. - How he views taking over from founder Fred Smith as a responsibility to protect the culture that Smith created. On his path to CEO - How a roommate’s canceled FedEx interview led