A broad review links nanomaterials, topological physics, and quantum computing to show how nanoscale engineering could help move quantum technologies from theoretical promise toward real-world applications. Review: From Nanotechnology to Topological Quantum Computers: An Interdisciplinary Leap. Image Credit: JLStock / Shutterstock A recent working paper published in the journal Cambridge Open Engage examines the convergence of nanotechnology, quantum physics, materials science, and advanced computing in the emerging era of quantum technologies. The review highlights how developments in topological materials, Majorana fermions, Weyl semimetals, and quantum simulations are informing possible routes toward fault-tolerant quantum computing and next-generation electronic systems. It also discusses the expanding role of nanomaterials in healthcare, energy storage, electronics, and environmental applications. Quantum Science Enters a New Technological Era Rapid advances in quantum science, nanotechnology, and materials engineering are accelerating the development of next-generation computing and multifunctional nanoscale systems. Conventional quantum computing platforms often face major limitations, such as decoherence, environmental instability, and poor scalability, that limit their practical implementation. To address these challenges, researchers are exploring topological quantum systems, Majorana fermions, Weyl semimetals, and low-dimensional nanomaterials that exhibit enhanced electronic stability, high carrier mobility, and potentially fault-tolerant quantum properties. This review systematically examines recent advances in topological materials, quantum architectures, and nanomaterial-based technologies that support the transition from theoretical quantum physics to practical engineering applications. It explains how Majorana-based topological qubits, semiconductor nanowires, and Weyl semimetals could improve quantum stability and computational reliability if key challenges in coherence, fabrication, and scalability are overcome. The review discusses the role of two-dimensional materials such as graphene, MoS2, and WS2 in enabling energy-efficient electronics, spintronic systems, flexible devices, and quantum optoelectronics. It also highlights the expanding applications of nanoparticles, carbon quantum dots, carbon nanotubes, and nanorods in nanomedicine, biosensing, imaging, targeted drug delivery, and water purification. Experimental Strategies and Computational